All along, the bioplastics packaging industry has been growing at two figures and is expected to grow further over the next ten years. This irreversible trend is related to the breakdown of human DNA resulting in increased drug efficacy and reduced side effects.
The gas barrier properties of the higher the main characteristics of high-end cycloolefin polymer has been further enhanced, without losing any original advantages, such as low adsorption and precipitation of metal ions, high transparency and high filtration performance. As for the gas barrier property, the oxygen barrier test on the new multilayer plastic bottle proves that the barrier level is superior to any existing plastic packaging material used for injection package. One of the special advantages of multilayer designs is higher damage resistance, due to the enhanced structure of polyamides with extremely high puncture resistance, and makes the packaging suitable for cytotoxic drug solutions.
In short, the unique properties of biological drugs, means that they need to seal the container system more complex, and the glass bottle as a conventional material, sometimes to the limit. Plastic polymers such as polyethylene and polypropylene are good substitutes for glass and can be used as primary packaging materials in many applications, such as solid and ophthalmic preparations and infusion preparations.
More comprehensive consideration is expected to make multi-layer plastic bottles no longer limited to the specialized use of injection containers. By virtue of its stability throughout the shelf life, safety in filling, transportation and operation, coupled with its economy, it will be more widely promoted. This will lead to the creation of packaging suitable for specific functional requirements of sensitive biological drugs, and will eventually make the drug more effective and safer.
However, these polymers are not ideal packaging materials for injection preparations due to lack of transparency and lack of gas barrier properties after disinfection of bioplastics.